Cerebral perfusion pressure optimization for the regulation of brain edema and intracranial pressure

Background: Increased intracranial pressure (ICP) is a pathological condition associated with severe neurological conditions in patients acute brain injuries. Managing increased ICP based on optimal cerebral perfusion (CPP) crucial for improving outcomes.Current Concepts: Cerebral autoregulation, the intrinsic ability to maintain stable blood flow across wide range of CPP, impaired several difference between mean arterial and ICP, critical factor maintaining flow. Therefore, CPP important managing In addition, monitoring autoregulation its response derangements can help diagnose, manage, predict injury outcomes. Goal-directed therapy using beneficial elevation. If excessively low patient elevated pressure, treatment increase should be considered as first step, called optimizing pressure. However, if high lower by controlling an appropriate level prevent worsening edema due hyperperfusion considered.Discussion Conclusion: Monitoring guide management may helpful goal-directed prognosis among